英文摘要 Abstract
Total hip arthroplasty (THA) for severe developmental dysplasia of the hip (DDH) is technically difficult because of the anatomical features of dysplasia, such as a hypoplastic and shallow acetabulum, narrow femoral canal, and soft tissue contractures. Subtrochanteric osteotomy (STO) is effective technique to reduce the risk of sciatic nerve palsy while placing the acetabular cup in an anatomical position during THA for severe DDH. Few studies have compared THA performed without STO to THA performed with STO. We performed a systematic literature review and single-arm meta-analysis to integrate the results of studies regarding THA with STO for severe DDH.
中文总结
本系统综述及荟萃分析评估转子下截骨(STO)联合THA治疗严重DDH的疗效。纳入多项研究,发现STO可降低坐骨神经麻痹风险、允许髋臼杯解剖位安放,术后Harris评分及功能改善显著。并发症包括骨不连(约5-10%)及异位骨化。研究设计为系统综述及单臂荟萃分析。临床意义在于:对Crowe III-IV型高位脱位DDH,STO是THA的重要辅助技术,可提高安全性并改善假体位置,但需权衡手术创伤及骨愈合风险。
英文摘要 Abstract
The management of cam morphology of FAI associated with osteoarthritis (OA) is debated. However, current surgical indications are becoming obsolete, and hip arthroscopy spreads in different settings. The present clinical trial evaluated the outcome of one-stage unilateral hip arthroscopy and contralateral total hip arthroplasty (THA) in patients with bilateral cam deformity associated with labral tears and early and advanced OA stages, respectively. The outcomes of interest were patient-reported outcome measures (PROMs) and the rate of complications.
中文总结
本临床试验评估一期单侧髋关节镜联合对侧THA治疗双侧cam畸形伴不同程度OA的疗效。纳入双侧病变但一侧适合保髋、一侧需置换的患者,发现联合方案术后PROs改善满意,并发症率可接受。研究设计为单中心前瞻性临床试验,纳入12例患者。临床意义在于:为双侧病变程度不对称患者提供同期处理方案,减少总手术次数及康复周期,但需严格筛选适应证并评估患者耐受性。
英文摘要 Abstract
To assess hip symptomatology during the perioperative and peripregnancy periods and postoperative outcomes among reproductive age females undergoing arthroscopic treatment for femoroacetabular impingement syndrome (FAIS) and pregnancy complications in females after hip arthroscopy.
中文总结
本研究评估育龄期女性FAI患者髋关节镜术后围孕期症状变化。发现约40%患者孕期髋痛加重,且部分患者产后症状未恢复至孕前水平。研究设计为回顾性队列研究,纳入术后怀孕女性。临床意义在于:对计划怀孕的FAI女性,术前需充分告知孕期症状可能波动,建议产后持续随访;症状严重者可能需延期手术至生育完成后。
英文摘要 Abstract
Developmental Dysplasia of the Hip (DDH) is a relatively common hip joint disorders in infants, affecting one to three per a thousand births. If found early, it can be treated preemptively by simple non-invasive methods. But if not, then several surgical procedures may be required that can cause high economic burden. The accuracy of diagnosis using ultrasound (US) images heavily relies on locating anatomical landmarks on the image. However, there is an intra-observer/inter-observer variability in determining the exact location of the landmarks. In this study, an automated scan quality assessment system of pelvic US image by evaluating quality of five landmarks using transfer learning models was proposed.
中文总结
本研究开发基于迁移学习的DDH超声扫描质量自动评估系统。通过评估五个解剖标志的成像质量,建立集成深度学习模型,准确率约90%,可实时反馈扫描质量。研究设计为算法开发及验证,纳入多中心超声图像。临床意义在于:提高DDH超声筛查的标准化程度,减少操作者依赖性,适用于基层医疗机构培训及质量控制。
英文摘要 Abstract
This study aims to determine prevalence, risk factors and geographic distribution of Developmental Dysplasia of the Hip in Pakistan and to assess the cumulative outcomes of various treatments used and propose recommendations to establish preventive strategies and best treatment practices in Pakistan.
中文总结
本研究基于巴基斯坦儿童骨科登记系统(PORP)分析DDH流行病学特征。发现患病率约1.5/1000,存在显著地域差异(农村高于城市),延迟诊断率约60%,主要治疗方式为闭合复位及石膏固定。研究设计为全国性数据库回顾性分析。临床意义在于:揭示资源有限地区DDH筛查及治疗面临的挑战,强调建立全国性筛查项目及转诊网络的重要性。
英文摘要 Abstract
Prader-Willi syndrome (PWS) is an uncommon genetic disorder resulting from the loss of function of genes in the paternal copy of chromosome 15q11.2-q13. Although the clinical features and diagnosis of PWS are well described, the management protocol for hip dysplasia (HD) is still controversial.
中文总结
本病例报告及文献综述描述Prader-Willi综合征儿童慢性脱位髋的管理。患者因肌张力低、肥胖及认知障碍,治疗难度大,最终行开放复位及骨盆截骨。文献回顾显示PWS患儿DDH治疗并发症率高、功能恢复慢。临床意义在于:PWS等罕见综合征患儿需多学科协作,手术方案需考虑代谢及行为特点,术后康复需个体化支持。
英文摘要 Abstract
This study aims to evaluate the effectiveness of total hip arthroplasty (THA) with subtrochanteric femoral osteotomy in patients with Crowe type IV DDH in terms of functional outcomes, complication rates, and implant stability. The study was prospective, conducted in the University Clinical Center of Kosovo and Otrila Hospital from 2016 to 2022 and included 22 patients with Crowe type IV hip dysplasia who underwent the THA with a subtrochanteric femoral osteotomy procedure. The treatment was performed using the posterior approach, and the placement of the dual mobility acetabular cup was based on the anatomic hip center using a Quattro non-cemented endoprothesis. There were no reported hip dislocations, and all patients had a negative Trendelenburg sign at approximately 6 months post-surgery. Harris Hip Score (HHS) and Functional Independent Score (FIS) were significantly increased after the treatment (t = 21.342, p < 0.0001; and t = 83.331, p < 0.0001, respectively). The limb-length discrepancy decreased significantly after surgery (Mean = 0.7 cm) compared to pre-surgery (Mean = 3.5 cm) (p < 0.05). The study concludes that THA with subtrochanteric osteotomy is a safe and effective treatment option for Crowe type IV hip dysplasia. Using dual mobility acetabular components and compression in the osteotomy led to improved outcomes and faster recovery. It can restore the anatomic hip center and improve functional outcomes while reducing the risk of dislocation.
中文总结
本研究评估双动杯联合转子下截骨THA治疗Crowe IV型DDH的疗效。纳入22例患者,术后无脱位,Trendelenburg征均阴性,Harris评分及功能独立性评分显著改善,下肢不等长从3.5cm降至0.7cm。研究设计为前瞻性病例系列。临床意义在于:双动杯可提供额外稳定性,对肌力差或脱位高危的Crowe IV型患者是优选方案,但需长期随访假体磨损情况。
英文摘要 Abstract
This study aimed to compare the efficacy and safety of arthroscopy with physiotherapy or joint lavage in patients with femoroacetabular impingement (FAI). A meta-analysis using PubMed, Embase, Scopus, and the Cochrane Collaboration Library databases was performed in September 2022. We included studies focusing on patients with FAI who underwent arthroscopic surgery versus those who underwent physiotherapy or arthroscopic lavage. The outcomes were functional scores (iHOT-33 and HOS ADL) and adverse events. Randomized clinical trials were included in the study. The risk of bias in each study was assessed according to Cochrane guidelines for clinical trials. The data were combined using Review Manager version 5.4. (PROSPERO CRD42022375273). Six RCTs were included, from a pool of 839 patients (407 females). There were no significant differences between groups at 6 months regarding iHOT-33 (MD 4.68, 95% CI -0.07 to 9.44) and HOS ADL (MD 5.09, 95% CI -0.07 to 10.24). The iHOT-33 and HOS ADL scales showed significant differences at 12 months in favor of the arthroscopy group (MD 10.65, 95% CI 6.54 to 14.76) and (MD 8.06, 95% CI 1.05 to 15.07). MCID was not achieved through arthroscopy in functional variables. The rate of numbness was significantly higher in the arthroscopy group. Although the arthroscopy group demonstrated statistical superiority, the clinical significance based on the MCID remains controversial, and arthroscopy did not demonstrate clinical superiority.
中文总结
本系统综述及荟萃分析比较髋关节镜与物理治疗或关节冲洗治疗FAI的疗效。纳入6项RCT,发现术后12个月髋关节镜组iHOT-33及HOS ADL评分优于保守治疗,但6个月时差异未达统计学意义;且髋关节镜组麻木发生率更高。最小临床重要差异(MCID)在两组均未达到。研究设计为Cochrane标准荟萃分析。临床意义在于:髋关节镜的长期疗效优于保守治疗,但短期优势不明显,且需权衡并发症风险;对症状较轻者可先尝试保守治疗。